L-arginine in Mitochondrial Encephalopathy, Lactic acidosis, and Stroke-like episodes: A Systematic Review

eSupplementary files: e1. Search strategy eFigure 1. Number of patients evaluated for safety and efficacy in Koga et al. 2018 eReferences eTable 2. Excluded studies after full-text review eTable3. Summary characteristics of included case reports and cohort study (N=34) eTable4. Summary characteristics of included open-label trials (N=3) eTable 5. Quality appraisal of case reports and case series eTable 6. Quality appraisal for all other non-randomised controlled trials eTable 7. PRISMA 2002 Checklist eTable 8. PRISMA 2020 for Abstracts Checklist eTable 9. PRISMA-S Checklist Raw data files: Summary data Clinical features Acute response