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Menin in complex with MI-1481

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Protein Data Bank Japan2023-10-04 更新2026-03-21 收录
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Menin in complex with MI-1481 Descriptor: 1,2-ETHANEDIOL, 4-methyl-1-{[(2S)-5-oxomorpholin-2-yl]methyl}-5-[(4-{[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino}piperidin-1-yl)methyl]-1H-indole-2-carbonitrile, DIMETHYL SULFOXIDE, ... Authors: Borkin, D, Klossowski, S, Pollock, J, Linhares, B, Cierpicki, T, Grembecka, J. Deposit date: 2017-12-19 Release date: 2018-11-28 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.82 Å) Cite: Complexity of Blocking Bivalent Protein-Protein Interactions: Development of a Highly Potent Inhibitor of the Menin-Mixed-Lineage Leukemia Interaction. J.Med.Chem., 61, 2018

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2017-12-19
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