CryoEM structure of the MDA5-dsRNA filament in complex with ADP with 88-degree helical twist

CryoEM structure of the MDA5-dsRNA filament in complex with ADP with 88-degree helical twist Descriptor: ADENOSINE-5'-DIPHOSPHATE, Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*AP*CP*GP*UP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*G)-3'), ... Authors: Yu, Q, Modis, Y. Deposit date: 2021-02-08 Release date: 2021-11-17 Last modified: 2024-07-10 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: MDA5 disease variant M854K prevents ATP-dependent structural discrimination of viral and cellular RNA. Nat Commun, 12, 2021