Late subsequent leukemia after childhood cancer: A report from the Childhood Cancer Survivor Study (CCSS)

The dataset contains all variables of interest presented in the study. By downloading and using these data, you agree that you will cite the appropriate publication in any communications or publications arising directly or indirectly from these data; for utilization of data available prior to publication, you agree to respect the requested responsibilities of resource users under 2003 Fort Lauderdale principles; you agree that you will never attempt to identify any participant. 

When using downloaded data, please cite corresponding paper and this repository:

Ghosh, T., Hyun, G., Dhaduk, R., Conces, M., Arnold, M. A., Howell, R. M., Henderson, T. O., McDonald, A., Robison, L. L., Yasui, Y., Ness, K. K., Armstrong, G. T., Neglia, J. P., & Turcotte, L. M. (2024). Late subsequent leukemia after childhood cancer: A report from the Childhood Cancer Survivor Study (CCSS). Cancer Medicine, 13(20). https://doi.org/10.1002/cam4.70086

Funding:

This work was supported by the National Cancer Institute (CA55727, G.T. Armstrong, Principal Investigator). Support to St. Jude Children’s Research Hospital also provided by the Cancer Center Support (CORE) grant (CA21765, C. Roberts, Principal Investigator) and the American Lebanese-Syrian Associated Charities (ALSAC).

Data dictionary:   

Sex: Sex of patientdxgroup: Diagnosis groupsplenectomy: Splenectomydxyrgrp: Diagnosis year grouplate_leukemia: Late Leukemia Categoriesage_dx: Age at Diagnosisagedxgrp: Age at Diagnosis Categoriesrace_ethgrp: Race/Ethnic groupanthgrp: Anthracycline groupepipgrp: Epipodophyllotoxin groupalkgrp: Alkylating agent grouppltgrp: Platinum agents groupradgrp: Radiation groupmaxrtdose: Maximum radiation dose to anybody region (Gy)livedead: Alive or deaddx_snleukemia: Years from primary to secondary diagnosis Categoriesdx_snleukemia_yr: Time from primary to secondary diagnosis (Years)a_snleukemia_grp: Age at leukemia diagnosis Categoriesa_snleukemia: Age at leukemia diagnosis (Years)survival_snleukemia: Survival after leukemia diagnosis (Years)surv_snleukemia_grp: Survival after leukemia diagnosis Categoriescause_mortality: Cause of Mortalityd_lcontact_org: Date of last contact (last questionnaire or death)u_causeicd10: Underlying cause of death (ICD10: 2007+ NDIu_causeicd9: Underlying cause of death (ICD9: 2002 NDI)causecat2002: Cause category (2002 NDI data only)deathinNDI: Death data from NDIa_dx: Age at diagnosisd_entry: Date of study entry (5 years from Date of diagnosis)a_entry: Age at study entrya_death: Age at deatha_fu1: Age at follow-up 1a_fu3: Age at follow-up 3a_fu6: Age at follow-up 6a_lcontact: Age at last contactfweight: Sampling weighthsct: Hematopoietic cell transplantationlate_leukemia_D1: Late Leukemia Grouplate_leukemia_D2: Very Late Leukemia Grouplineage: Cell Lineagesmk_status: Smoking Statusleukemia_dx: Leukemia Diagnosis Categories