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The crystal structure of H-Ras and SOS in complex with ligands

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Protein Data Bank Japan2024-05-08 更新2026-03-21 收录
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The crystal structure of H-Ras and SOS in complex with ligands Descriptor: 4-METHOXY-N-(1,3-THIAZOL-2-YL)BENZENESULFONAMIDE, GTPASE HRAS, SON OF SEVENLESS HOMOLOG 1 Authors: Winter, J.J.G, Anderson, M, Blades, K, Brassington, C, Breeze, A.L, Chresta, C, Embrey, K, Fairley, G, Faulder, P, Finlay, M.R.V, Kettle, J.G, Nowak, T, Overman, R, Patel, S.J, Perkins, P, Spadola, L, Tart, J, Tucker, J, Wrigley, G. Deposit date: 2014-07-02 Release date: 2015-03-04 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.83 Å) Cite: Small Molecule Binding Sites on the Ras:SOS Complex Can be Exploited for Inhibition of Ras Activation. J.Med.Chem., 58, 2015
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2014-07-02
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