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Crystal structure of human FPPS in ternary complex with YS0470 and inorganic pyrophosphate

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Protein Data Bank Japan2023-09-20 更新2026-03-21 收录
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Crystal structure of human FPPS in ternary complex with YS0470 and inorganic pyrophosphate Descriptor: Farnesyl pyrophosphate synthase, MAGNESIUM ION, PYROPHOSPHATE 2-, ... Authors: Park, J, Lin, Y.-S, Tsantrizos, Y.S, Berghuis, A.M. Deposit date: 2012-09-18 Release date: 2012-12-26 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.02 Å) Cite: Ternary complex structures of human farnesyl pyrophosphate synthase bound with a novel inhibitor and secondary ligands provide insights into the molecular details of the enzyme's active site closure. Bmc Struct.Biol., 12, 2012

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2012-09-18
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