Additional file 3 of A potential role for intragenic miRNAs on their hosts' interactome

Additional file 3: Evaluation of Target Prediction Methods. Based on protein and mRNA expression measurements in miRNA transfection experiments, we evaluated the target prediction methods used in this study, as well as prediction agreement as a method of its own. We estimated sensitivity, specificity, and AUC for target prediction methods used and prediction agreement based on the Selbach data [74] for changes in mRNA and protein expression after miRNA overexpression. (XLS 41 KB)