A novel capsule-mediated virulence mechanism in a bacterial pathogen. Bordetella pertussis
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA263207
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资源简介：
Bordetella pertussis, the causative agent of whooping cough, produces a microcapsule at its surface but its role in pertussis pathogenesis remained to be investigated.Absence of KpsT, a membrane-associated protein involved in the polysaccharide transport resulted in the down-modulation of a large number of virulence genes which correlated with strong attenuation in vivo. Overall design: One condition experiment, DeltaKpsT against WT. Biological replicates: 3 control replicates, 3 mutants replicates.
创建时间：
2014-10-06
