Survival of atopic Nc/Nga mice immunized with MVA or Dryvax after a lethal intranasal challenge with VACV strain WR.

Mean day of death and weights of spleens and lungs at death or at sacrification 14 days after the challenge are indicated. SD, standard deviation;*, dead mice were males;†, weight of normal spleens of age-matched mice is 70–80 mg;‡, weight of normal lungs of age-matched mice is 140–170 mg. Results of 2 independent experiments performed for each virus strain together with the PBS controls.Survival of atopic Nc/Nga mice immunized with MVA or Dryvax after a lethal intranasal challenge with VACV strain WR.