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Precision digital mapping of genomic DSBs by INDUCE-seq

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NIAID Data Ecosystem2026-03-12 收录
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We have developed INDUCE-seq, which simultaneously detects the presence of low-level endogenous DSBs caused by physiological processes, and higher-level recurrent breaks induced by restriction enzymes or CRISPR-Cas9 nuclesase. INDUCE-seq exploits an innovative NGS flow-cell enrichment method, permitting the digital detection of breaks in the genome.

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2021-03-01
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