Number and percentage of genes annotated with the indicated KEGG pathway or PIR tissue specificity term enriched in different HK and TS gene sets.

aHKera score-sorted MR genes were divided into 4 HK sets (HKI-HKIV) and 2 TS sets (TSI and TSII), each containing ∼2,000 genes (see Methods). bThe p values for the KEGG pathway were estimated using the Boferroni correction method by controlling the family-wide false discovery rate (FDR) under 5%. An additional criterion, gene number >10, was used to screen for genes enriched in the gene set with PIR tissue specificity annotations [37].