MacroH2A2 modulates the self-renewal of glioblastoma cells
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https://www.ncbi.nlm.nih.gov/sra/SRP394116
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资源简介:
Self-renewal is a crucial property of glioblastoma cells and is enabled by the choreographed function of chromatin regulators and transcription factors. Identifying targetable epigenetic mechanisms of self-renewal could represent an important step toward developing new and effective treatments for this universally lethal cancer. Here we uncover a targetable epigenetic axis of self-renewal mediated by the histone variant macroH2A2. Overall design: ChIP-seq of macroH2A2-FLAG in endogenously tagged primary glioblastoma cells
创建时间:
2023-08-26



