Targeting Krebs-cycle-deficient renal cell carcinoma with Poly ADP-Ribose Polymerase inhibitors and low-dose alkylating chemotherapy
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https://www.ncbi.nlm.nih.gov/sra/SRP370932
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资源简介：
In this study, we evaluated novel treatment approaches in newly generated models of FH- and SDHB-deficient RCC. CRISPR/Cas9 was used to engineer isogenic Fh1- and Sdhb-deficient murine models of RCC. RNA-Seq was used to profile this model. Overall design: RNA-Seq was performed on RENCA parental cells in comparison to FH1 & SDHB knockout cells. Two biological replicates were performed for each cell line.
创建时间：
2022-04-21
