Effect of antimicrobial peptides on field parasites and mosquitoes.

Peptides (final concentration of 50 µM) were mixed with human blood containing P. falciparum parasites from gametocyte carriers in the village of Nyaganabougou. This was membrane-fed to the progeny of An. gambiae mosquitoes collected from neighbouring areas. For each replicate, oocyst prevalence (number of oocyst positive mosquitoes, total number in parentheses) and oocyst intensity (mean number of oocysts present per gut, range in parentheses) were recorded. An equivalent volume of water without peptide was used for the control. N/D indicates not determined. N/S indicates non-significance.