Effect of repeated blood injections on clinical parameters of mice¹.

1Each experimental group was n = 5. 2Analysis of organ weight was performed using two factor-ANOVA test followed by Bonferroni post test. Differences were considered significant if P<0,05. Values reported are the probability of the difference in weight with respect to day 0. In italics groups that differed significantly from control at day 0. 3ALT: Alanine aminotransferase; BUN: Blood Urea Nitrogen; AST: Aspartate aminotransferase; TBIL: Total bilirrubine; TP: Total protein. Analysis of biochemical markers in serum was conducted using a general linear model multivariate contrast of means followed by a bilateral Dunnett's t test. In italics groups that differed significantly from control at day 0. 4NS: Not significant.