Retriever_POMC_phenotypes_2023

Data are results from experiments in which we measured phenotypes including weight, adiposity, food motivation, blood pressure, energy expenditure in Labrador and flatcoat retriever dogs with and without a mutation in the gene POMC which was previously described in Raffan 2016 (PMID: 27157046).
Each worksheet in the excel file can be exported as plain text for analysis with accompanying code. In addition there is a README tab with experimenter contact information, and a Participation Summary sheet which shows which dogs took part in the different experiments.
FCR_epi and RCR_epi_readme: Flatcoat retriever epidemiology information and data.
EndocrineTests: Results of ACTH, TT4, TSH
BP: Blood pressure data
EnergyExp: indirect calorimetry data from FCR
FoodPreference, AdLibitum, IncentiveSalience: data from different eating behaviour experiments.

本数据集汇聚了针对拉布拉多犬和平毛寻回犬进行的实验结果，其中测量了包括体重、脂肪含量、食物动机、血压和能量消耗等表型特征，并区分了是否携带POMC基因突变的情况。该基因突变在Raffan于2016年的研究中已有描述（PMID: 27157046）。Excel文件中的每个工作表均可导出为纯文本格式，以便与配套代码一同进行分析。此外，还包括README标签页，其中包含了实验者的联系方式，以及参与不同实验的犬只参与情况概览。FCR_epi和RCR_epi_readme标签页提供了平毛寻回犬的流行病学信息和数据。EndocrineTests标签页包含了ACTH、TT4、TSH的检测结果。BP标签页记录了血压数据。EnergyExp标签页则收录了来自平毛寻回犬的间接热量计数据。FoodPreference、AdLibitum、IncentiveSalience标签页则展示了不同饮食习惯实验的数据。