Multi-centre extraction and sequencing of IBD mucosal microbiome
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Assessment of inter-laboratory variation in the characterization and analysis of the mucosal microbiota in Crohn's disease and ulcerative colitis
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创建时间：
2020-06-09
相关数据集
Longitudinal Multi’omics of the Human Microbiome in Inflammatory Bowel Disease. Longitudinal Multi’omics of the Human Microbiome in Inflammatory Bowel Disease
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We have performed 16S sequencing experiment on faecal samples obtained from 30 individuals (9 Crohn's disease patients, 11 ulcerative colitis (UC) patients and 10 healthy volunteers). In this study, we examined the imbalance in the gut microbiota in IBD patients compared to healthy volunteers. We find that the gut microbiota of IBD patients is less biodiverse than healthy individuals. Also, the changes are mainly in 4 most abundant phyla including Firmicutes, Bacteroidetes, Actinobacteria and Proteobacteria.. Microbial imbalance in inflammatory bowel disease patients at different taxonomic levels
Background: Inflammatory bowel disease (IBD), is a debilitating group of chronic diseases including Crohn’s Disease (CD) and ulcerative colitis (UC), which causes inflammation of the gut and affects m
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Recent studies show that the intestinal microbiota of patients with CD is enriched by adherent-invasive E. coli. The aim of this study was to characterize the diversity of E. coli strains in human fec
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An analysis of the composition of viruses and bacteria in stool samples from IBD patients and healthy controls.. IBD Virome
Decreases in the diversity of enteric bacterial populations are observed in patients with Crohn’s disease (CD) and ulcerative colitis (UC). Less is known about the virome in these diseases. We show th
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Intestinal microbial profile of UC and CD patients
We investigate how specific differential gut microbiota interact with the host and participate in the efficacy of biologics.
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