Bruton's tyrosine kinase in complex with covalent inhibitor compound 27
收藏Protein Data Bank Japan2024-10-16 更新2026-05-24 收录
下载链接：
https://pdbj.org/mine/summary/8tu5
下载链接
链接失效反馈官方服务：
资源简介：
Bruton's tyrosine kinase in complex with covalent inhibitor compound 27 Descriptor: 1-[(1S,5S,6S)-6-methyl-6-{[(6M,8R)-6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl]oxy}-2-azabicyclo[3.2.0]heptan-2-yl]propan-1-one, Tyrosine-protein kinase BTK Authors: Metrick, C.M. Deposit date: 2023-08-15 Release date: 2024-06-26 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Discovery and Preclinical Characterization of BIIB129, a Covalent, Selective, and Brain-Penetrant BTK Inhibitor for the Treatment of Multiple Sclerosis. J.Med.Chem., 67, 2024
创建时间：
2023-08-15
