Review about Unlocking natural cross-link agents for biopolymer wound dressings

1. General Information- **Data Set Title**: Review about Unlocking natural cross-link agents for biopolymer wound dressings- **Authors**: - Principal investigator and contact person: Dorota Chełminiak-Dudkiewicz, Nicolaus Copernicus University in Torun, e-mail: [e-mail].-Investigator: Aji Suhartoyo, Nicolaus Copernicus University in Torun, e-mail:[e-mail]- **Date of data collection**: year 2025.- **Place of data collection**: Torun- **Keywords***: Biopolymer crosslinking; Industrial crops; Wound dressings; Bio-based polymers; Ethnobotanical agentsData language**: English- **Sources of funding**: National Science Center (NCN) competition: SONATA 18- UMO-2022/47/D/NZ7/01821.2. Overview of data and files- **File List**:Fig.1.tiff: according to (Chelminiak-Dudkiewicz et al., 2024), the study showcases a biopolymer for wound dressing using natural cross-link agents. The illustration presents the chemical structures of two natural derived compounds: one derived from cannabis (left) and another from a crab(right). These compounds are combined to create the biopolymer (CanO-VioL)CS, which is present in the center. This figure emphasizes the potential of natural sources in advancing biopolymer applications for medical use.Fig.2. tiff: Temporal trend of scientific publications contributing to the subject Natural Cross-link Agents for Biopolymer (Search carried out in Scopus(blue) and Web of Science(pink) on February 4th, 2025).Fig.3.tiff: Illustration wound care enhances wound healing stages. Four stages are illustrated: haemostasis, inflammation, proliferation, and remodelling.Fig.4.tiff: illustrating the network map of the co-occurrence keywords concerning natural cross-link agents in biopolymers for wound dressing. As postulated by (Kirby, 2023), VOSviewer is described as an open-source software used to develop bibliometrics relations of different variables. This approach makes constructing, displaying, and navigating the bibliometric maps easier (Han et al., 2011).Fig.5.tiff: Chemical structure of Tannins: a. The general structure of tannins, b. The basic structure of gallotannin, c. The structure of condensed tannin.Fig.6.tiff: Schematic diagram of the scheme on the cross-linking mechanism of a) NO-TA and b) OX-TA.Fig.7.tiff: Illustration of cross-linked poly(tannic acid) hydrogel process.Fig.8.tiff: Schematic diagram of Pectin structure and the source of it.Fig.9.tiff: Schematic diagram Citric Acid creation, structure and end substance.Fig.10.tiff: Illustration of citric acid as the cross-linker.Fig.11.tiff: Molecular structure of Gellan gum.Fig.12.tiff: Illustration of the reaction involving the cross-link of high acetyl gellan gum and chitosan polymers, adopted from (Sabadini et al., 2015).Fig.13.tiff: Schematic diagram of Curcumin structure and source.Fig.14.tiff: illustration: a) black rot caused by the bacterium Xanthomonas campestris in crucifer crops as a resource of xantham gum and b) xantham gum structure.Fig.15.tiff: Structures of monosaccharides from KGP.Fig.16.tiff: The mechanism of action of the wound healing properties of KGPs.Fig.17.tiff: KGPs distribution (Kaempferia galanga L. | Plants of the World Online | Kew Science, access on 6th Dec 2024).Fig.18.tiff: Fig distribution Ficus carica L. | Plants of the World Online | Kew Science access on 6th Dec 2024).Fig.19.tiff: The most common monosaccharide components in FIG.Fig.20.tiff: Melissa officinalis distribution Melissa officinalis L. | Plants of the World Online | Kew Science access on 6th Dec 2024).Fig.21.tiff: Schematic diagram illustrating Melissa officinalis as an active substance against microbial activity test.Fig.22.tiff: Myrothamnus flabellifolius distribution Myrothamnus flabellifolius Welw. | Plants of the World Online | Kew Science access on 6th Dec 2024).Fig.23.tiff: Illustration to obtain monosaccharide composition in Myrothamnus flabellifolius leaf cell walls.Fig.24.tiff: Musa distribution Musa L. | Plants of the World Online | Kew Science access on 6th Dec 2024).Fig.25.tiff: Schematic illustration of a Musa sapientum biofilm.- **File formats**: tiff3. sharing and access information- **Licenses/Restrictions**: CC BY - Creative Commons Attribution 4.0. - **Related Publications**: https://www.sciencedirect.com/science/article/pii/S0926669025007617