Genomic imbalances of lung cancer
收藏NIAID Data Ecosystem2026-03-09 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE89927
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The array comparative genomic hybridization (aCGH) was perform to identify regions with genomic imbalance in lung cancer.The aCGH analysis detected a total of 325 regions with genomic imbalance in all 8 lung cancer samples, ranging from focal rearrangements (70 kb–5 Mb) to chromosome-arm alterations with chromosomal segments amplification or deletion. Among these mutations, a total of 115 genomic imbalances were discovered occurring at high frequency varying from 25% to 50%. Genomic imbalances of lung cancer was tested in 8 randomly-selected pairs of lung cancer tissue and adjacent normal tissues using the Agilent SurePrint G3 human CGH 4×180K array by a commercial company
创建时间:
2016-11-21



