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Transcription factor NFAT1 regulates systemic autoimmunity through modulation of dendritic cell property

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE92593
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To characterize the roles of NFAT1 in the pathogenesis of autoimmune myasthenia gravis (MG) at a genome-wide scale, we performed gene expression microarray analysis for wild-type (WT) and NFAT1 KO bone marrow-derived dendritic cells (BMDCs) with or without 2h and 12h-stimulation with pam3CSK4. Total RNA was extracted from bone marrow derived dendritic cells of WT and NFAT1 KO with or without pam3CSK4 stimulation
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2018-06-14
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