Additional file 3: Table S1. of Multi-omic measurement of mutually exclusive loss-of-function enriches for candidate synthetic lethal gene pairs

Output from the CCLE genomic workflow (BEEM) and mapping to genes from the Hoffman epigenetic screen, the Costanzo yeast screen and known tumour suppressor genes. Table S2. Output from the CCLE expression (BiGEE) workflow and mapping to genes from the Hoffman epigenetic screen, the Costanzo yeast screen and known tumour suppressor genes. Table S3. Output from the copy genomic (BEEM) workflow and mapping to genes from the Hoffman epigenetic screen, the Costanzo yeast screen and known tumour suppressor genes. Table S4. Epigenetic Analysis: Genomic workflow (BEEM). Table S5. Epigenetic Analysis: Expression workflow (BiGEE). Table S6. Output from the gene expression workflow (BiGEE) mapped to genes from the Lu et al. publication. Table S7. Output from the gene expression workflow (BEEM) mapped to genes from the Lu et al. publication. Table S8. Output from the LUAD Genomic (BEEM) workflow and mapping to genes from the Hoffman epigenetic screen, the Costanzo yeast screen and known tumour suppressor genes. Table S9. Output from the LUAD expression (BiGEE) workflow and mapping to genes from the Hoffman epigenetic screen, the Costanzo yeast screen and known tumour suppressor genes. Table S10. Simulation results for the likelihood method (p value), Kurtosis method (p value), bimodal index (1.1â 1.5) and BIG (BiSEp) (p value). (XLSX 8250 kb)