Additional file 1 of Integrative analysis of mutated genes and mutational processes reveals novel mutational biomarkers in colorectal cancer

Additional file 1: Table S1. List of 382 significantly mutated genes that were identified by negative-binomial distribution. Table S2. List of 3131 significantly mutated gene-motifs that were identified by beta-binomial distribution. Table S3. List of CRC patients that were grouped in each subtype using a model-based clustering. Table S4. Frequency of mutation in 3131 significantly mutated gene-motifs in each subtype. Table S5. Subtype-specific genes that were identified by a Fisher exact test. Rare mutated genes in each subtype also highlight by green color. Table S6. List of protein-coding genes that become a significant gene in different subtypes but with enrichment of mutations in different motif context. Table S7. Fraction of mutations in different transcripts of candidate genes in each subtype. Table S8. Gene ontology analysis from WebGestalt tool [61] on 50 highly mutated coding genes in each subtype. We only considered those ontology terms with FDR