Chromatin opening on CBFA2T3::GLIS2 iPSC-derived progenitors
收藏ChEBI2025-07-09 更新2026-07-12 收录
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资源简介：
Chromatin opening on CBFA2T3::GLIS2 iPSC-derived progenitors
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创建时间：
2025-07-09
相关数据集
Chromatin opening on CBFA2T3::GLIS2 iPSC-derived progenitors
Wild-type (CTRL) and CBFA2T3::GLIS2 induced pluripotent stem cell (iPSC) clones were differentiated into hematopoietic cells in vitro. Cells from day 13 in vitro differentiation were analysed. In addi
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Transcriptional effect of CBFA2T3::GLIS2 oncogenic fusion engineering by CRISPR-Cas9 in iPSC-derived hematopoietic cells
inv(16)(p13.3;q24.2) leading to the ETO2-GLIS2 fusion was engineered in iPSC cells. iPSC were then differentiated toward hematopoietic lineage and engrafted in immunodeficient recipient mice. Cells ar
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ChIP-seq to identify binding sites of the fusion oncogene CBFA2T3::GLIS2 in WSU-AML cell line
ChIP-seq to identify binding sites of the fusion oncogene CBFA2T3::GLIS2 in WSU-AML cell line
ChEBI2025-07-09 更新00
Transcriptional effect of CBFA2T3::GLIS2 oncogenic fusion engineering by CRISPR-Cas9 in iPSC-derived hematopoietic cells
Transcriptional effect of CBFA2T3::GLIS2 oncogenic fusion engineering by CRISPR-Cas9 in iPSC-derived hematopoietic cells
ChEBI2025-07-09 更新00
CBFA2T3::GLIS2 pediatric acute megakaryoblastic leukemia is sensitive to BCL-XL inhibition by navitoclax and DT2216. CBFA2T3::GLIS2 pediatric acute megakaryoblastic leukemia is sensitive to BCL-XL inhibition by navitoclax and DT2216
We engineered human models of CBFA2T3::GLIS2 acute megakaryoblastic leukemia and compared gene expression profiles to primary pediatric samples. Overall design: RNA sequencing of human models of CBFA2
NIAID Data Ecosystem60
