Crystal structure of Cryptosporidium parvum Thioredoxin Reductase in complex with the auranofin analogue AuP(OCH3)3Cl

Crystal structure of Cryptosporidium parvum Thioredoxin Reductase in complex with the auranofin analogue AuP(OCH3)3Cl Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, GOLD ION, Thioredoxin reductase Authors: Gabriele, F, Palerma, M, Ardini, M, Bogard, J, Williams, D.L, Ippoliti, R, Angelucci, F. Deposit date: 2025-06-20 Release date: 2026-06-03 Last modified: 2026-06-10 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Gold-containing compounds target an apicomplexan Thioredoxin reductase: Disclosing reactivity through structural and functional characterization. Int.J.Biol.Macromol., 369, 2026