Microbiology of Molar–Incisor Hypomineralization lesions

An insufficient mineralization (hypomineralization) in the teeth during the maturation stage of amelogenesis cause defects in 3-44% of children. Here, we describe for the first time the microbiota associated to these defects and compared it to healthy teeth within the same subjects.Supragingival dental plaque of patients with Molar–Incisor Hypomineralization (MIH) was sampled from healthy and affected teeth from the same mouth of 23 children. Total DNA was extracted and the 16S rRNA gene was sequenced by Illumina sequencing in order to describe the bacterial composition.