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TNFa-stimulation of XIAP -/- MEF

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE3700
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资源简介:
XIAP (X chromosome-linked inhibitor of apoptosis; ILP, BIRC4) is involved not only in apoptosis, but also in signal tranduction in the NF-kappaB, TGF-beta, bone morphogenic protein, and JNK signalling pathways. We have analyzed whether XIAP deletion leads to changes in gene expression, particularly after inflammatory stimulation. Keywords: genetic modification, inflammatory response Fibroblasts from wild-type and XIAP knockout mice were analyzed with and without TNFa stimulation (4 hours) using Affymetrix U74Av2 arrays.
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2018-02-18
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