Crystal structure of an activated (Thr->Asp) Polo-like kinase 1 (Plk1) catalytic domain in complex with Compound 041
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Crystal structure of an activated (Thr->Asp) Polo-like kinase 1 (Plk1) catalytic domain in complex with Compound 041 Descriptor: 3-[3-chloro-5-(5-{[(1S)-1-phenylethyl]amino}isoxazolo[5,4-c]pyridin-3-yl)phenyl]propan-1-ol, Polo-like kinase 1 Authors: Elling, R.A, Hanan, E.J, Lew, W, Romanowski, M.J. Deposit date: 2008-05-30 Release date: 2008-10-07 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (3.15 Å) Cite: Design and synthesis of 2-amino-isoxazolopyridines as Polo-like kinase inhibitors. Bioorg.Med.Chem.Lett., 18, 2008
创建时间：
2008-05-30
