Synthesis of Spiro[indole-3,5′-isoxazoles] with Anticancer Activity via a Formal [4 + 1]-Spirocyclization of Nitroalkenes to Indoles
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https://figshare.com/articles/dataset/Synthesis_of_Spiro_indole-3_5_-isoxazoles_with_Anticancer_Activity_via_a_Formal_4_1_-Spirocyclization_of_Nitroalkenes_to_Indoles/8153870
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资源简介：
An
acid-assisted [4 + 1]-cycloaddition of indoles with nitrostyrenes
affords 4′H-spiro[indole-3,5′-isoxazoles]
in a diastereomerically pure form. Several of these spirocyclic molecules
exhibit promising anticancer activity by reducing viability and inducing
differentiation of neuroblastoma cells.
创建时间：
2019-05-09
