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Cryo-EM structure of nanodisc-reconstituted wildtype human MRP4 (in complex with topotecan)

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Protein Data Bank Japan2023-11-15 更新2026-03-28 收录
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https://pdbj.org/mine/summary/8bwq
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Cryo-EM structure of nanodisc-reconstituted wildtype human MRP4 (in complex with topotecan) Descriptor: (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE, ATP-binding cassette sub-family C member 4 Authors: Raj, I, Bloch, M, Pape, T.H, Taylor, N.M.I. Deposit date: 2022-12-07 Release date: 2023-08-30 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Structural and mechanistic basis of substrate transport by the multidrug transporter MRP4. Structure, 31, 2023
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2022-12-07
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