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Identification of genes upregulated and downregulated in transformed cells (TCs) derived upon Atoh8 depletion

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NIAID Data Ecosystem2026-03-14 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP241825
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Upon Atoh8 downregulation by shRNA in MEFs, KRas512D mutation c-Myc over-expression and depletion of p53 were induced in mouse embryonic fibroblasts. After 10 passages, cells were collected and RNA extracted. Overall design: Comparison of transcriptomes of sh#control TCs and sh#Atoh8 TCs 10 passages after malignant transformation induction.
创建时间:
2022-10-05
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