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Hepatic stellate cell single cell atlas reveals a highly similar activation process across liver disease aetiologies

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP532019
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It is still unclear whether hepatic stellate cells (HSC) activate in a similar manner in different chronic liver disease aetiologies. Here, we investigate how human stellate cells activate in vitro at the transcriptome level. Overall design: Ultrapure primary human HSCs were isolated by FACS (excitation: 355 nm, emission: 450 nm) (n = 4) and compared with plated primary human HSCs after 1 (n = 3) and 3 passages (n = 3).
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2025-01-25
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