Crystal structure of factor Xa in complex with 43 Descriptor: CALCIUM ION, COAGULATION FACTOR X, FACTOR XA, ... Authors: Nazare, M, Will, D.W, Matter, H, Schreuder, H, Ritter, K, Urmann, M, Essrich, M
We herein report the conventional and microscale parallel synthesis of selective inhibitors of human blood coagulation factor XIIa and thrombin exhibiting a 1,2,4-triazol-5-amine scaffold. Structural
Factor XIa in Complex with Compound 2g Descriptor: 3-chloranyl-4-[1-[(1~{R})-1-[5-[3-chloranyl-2-fluoranyl-6-(1,2,3,4-tetrazol-1-yl)phenyl]-1-oxidanyl-pyridin-2-yl]-2-cyclopropyl-ethyl]pyrazol-4-yl]-5
Haemadipsa yanyuanensis is a terrestrial blood-feeding leech with underexplored anticoagulant adaptations. Here, we present its first chromosome-level genome assembly (165.32 Mb, 9 chromosomes; BUSCO