metabolic data.xlsx

Using the wide range of targeted technologies and a combination of means (UPLC-MS/MS detection platform, self-built database, and multivariate statistical analysis), the addition of SBS was found to restore the levels of metabolites pathways (e.g., L-malic acid, N-acetyl-aspartic acid, N-acetyl-l-alanine, etc.) in rats, which means that the metabolic damage induced by CCl₄was alleviated.本研究采用多类靶向技术并结合多种检测分析手段（超高效液相色谱-串联质谱（UPLC-MS/MS）检测平台、自建数据库与多变量统计分析方法），经分析发现补充SBS可使大鼠体内代谢通路相关代谢物的水平（如L-苹果酸（L-malic acid）、N-乙酰天冬氨酸（N-acetyl-aspartic acid）、N-乙酰-L-丙氨酸（N-acetyl-L-alanine）等）恢复正常，这表明四氯化碳（CCl₄）诱导的代谢损伤得到有效缓解。