Figure S1 - The Mechanism of Calcium-Induced Inhibition of Muscle Fructose 1,6-bisphosphatase and Destabilization of Glyconeogenic Complex
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Ca2+-induced dissociation of FBPase from sarcomeric structures is not a result of destabilization of aldolase binding to these structures. In the presence of 200 µM Ca2+, binding of the FITC-labeled Tyr57Trp FBPase mutant to sarcomeric structures is disturbed (A) whereas aldolase still localizes on the Z-line (B). Bar = 5 µm. (DOC)
创建时间:
2015-12-02



