Additional file 3 of Prognostic value of the micronucleus assay for clinical endpoints in neoadjuvant radiochemotherapy for rectal cancer

Additional file 3: Suppl. Figure 3. a-b. There was no correlation between patient survival and lymphocyte cytogenetic damage. The Kaplan-Meier survival curves depict the cancer-specific survival (Suppl. Fig. 3a), the recurrence-free survival, the local recurrence-free survival, and the distant metastasis-free survival (Suppl. Fig. 3b). Patients were stratified according to the median of micronuclei (MN) or of nucleoplasmatic bridges (NPB), respectively, counted in binucleated lymphocytes (BNL/BL) after 50.4 Gy of radiochemotherapy (RCT). The endpoint for cancer-specific survival was any death related to tumor recurrence. Significance tests were performed using the Cox proportional hazards model.