Additional file 1 of Genetic evidence for a causal relationship between type 2 diabetes and peripheral artery disease in both Europeans and East Asians

Additional file 1: Table S1. ICD codes of PAD and T2D. Table S2. MR results between T2D and PAD in Europeans. Table S3. MR results between T2D and PAD in Europeans (without excluding potential pleiotropy SNPs). Table S4. MVMR results between T2D and PAD adjusted by potential risk factors in Europeans. Table S5. Summary of PRS regression of PRS for T2D on PAD status in Europeans. Table S6. Summary of PRS regression of PRS for PAD on T2D status in Europeans. Table S7. Novel SNPs underlying the shared genetics of T2D and PAD in Europeans detected by MTAG. Table S8. Candidate genes associated with comorbid T2D and PAD in Europeans detected by MAGMA. Table S9. Significant SMR associations of gene expression (from Table S8) with T2D, PAD, and their cross-trait. Table S10. MR results between T2D and PAD in East Asians. Table S11. MR results between T2D and PAD in East Asians (without excluding potential pleiotropy SNPs). Table S12. MVMR results between T2D and PAD adjusted by potential risk factors in East Asians. Table S13. Summary of PRS regression of PRS for T2D on PAD status in East Asians. Table S14. Summary of PRS regression of PRS for PAD on T2D status in East Asians. Table S15. Candidate genes associated with comorbid T2D and PAD in East Asians detected by MAGMA. Table S16. Significant SMR associations of gene expression (from Table S15) with T2D, PAD, and their cross-trait. (XLS 383 kb)