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Crystal structure of CYP3A4 bound to an inhibitor

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Protein Data Bank Japan2025-03-05 更新2026-04-19 收录
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Crystal structure of CYP3A4 bound to an inhibitor Descriptor: (2R)-2-{[(2S)-2-(benzenesulfonamido)-3-phenylpropyl]sulfanyl}-3-phenyl-N-[3-(pyridin-3-yl)propyl]propanamide, Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE Authors: Sevrioiukova, I.F. Deposit date: 2024-07-17 Release date: 2025-01-08 Last modified: 2025-03-05 Method: X-RAY DIFFRACTION (2.81 Å) Cite: Evaluation of Larger Side-Group Functionalities and the Side/End-Group Interplay in Ritonavir-Like Inhibitors of CYP3A4. Chem.Biol.Drug Des., 105, 2025

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2024-07-17
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