Early-life stress of Cntnap2 heterozygous mice demonstrates a gene by environment interaction model for developmental brain disorders
收藏Alliance of Genome Resources2026-08-01 收录
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We examined whether adult heterozygous mice (Cntnap2+/-; phenotypically normal) subjected to an early-life stress would have social-related deficits and disruptions in 5-hydroxymethylcytosine (5hmC), similar to the Cntnap2-/-. Profiled genome-wide 5hmC and RNA expression in the striatum of prenatal stressed and non-stressed mice that were wild type or heterozygous for the Cntnap2 gene
