Structure of CXCR3 in complex with VUF11418 (Receptor-ligand focused map)

Structure of CXCR3 in complex with VUF11418 (Receptor-ligand focused map) Descriptor: C-X-C chemokine receptor type 3, [(1~{R},5~{S})-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]methyl-[[4-(2-iodanylphenyl)phenyl]methyl]-dimethyl-azanium Authors: Sano, F.K, Saha, S, Sharma, S, Ganguly, M, Shihoya, W, Nureki, O, Shukla, A.K, Banerjee, R. Deposit date: 2024-01-22 Release date: 2025-02-26 Last modified: 2025-04-09 Method: ELECTRON MICROSCOPY (3.53 Å) Cite: Structural visualization of small molecule recognition by CXCR3 uncovers dual-agonism in the CXCR3-CXCR7 system. Nat Commun, 16, 2025