Crystal Structure of PDE5A1 catalytic domain in complex with Vardenafil
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Crystal Structure of PDE5A1 catalytic domain in complex with Vardenafil Descriptor: 2-{2-ETHOXY-5-[(4-ETHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-5-METHYL-7-PROPYLIMIDAZO[5,1-F][1,2,4]TRIAZIN-4(1H)-ONE, cGMP-specific 3',5'-cyclic phosphodiesterase Authors: Huanchen, W, Mengchun, Y, Howard, R, Sharron, H.F, Hengming, K. Deposit date: 2007-10-19 Release date: 2008-05-20 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.07 Å) Cite: Conformational variations of both phosphodiesterase-5 and inhibitors provide the structural basis for the physiological effects of vardenafil and sildenafil. Mol.Pharmacol., 73, 2008
创建时间：
2007-10-19
