In order to study the NK cell dependant immunoediting of carcinogen-induced fibrosarcomas, we studied the transcriptome of primary tumor grown in wt or NK cell deficient mice bulk mRNA sequencing of p

NIAID Data Ecosystem60

Association between HPK1 expression and T-cell exhaustion. Association between HPK1 expression and T-cell exhaustion

肿瘤免疫学

T细胞耗竭

We aimed to investigate the association between HPK1 expression and exhausted status of tumor. Overall design: Bulk RNA-seq was performed on fresh-frozen tissue samples of renal cell carcinoma.

NIAID Data Ecosystem60

Transcriptome analysis of tumor infiltrating NK and T cells in CT26-bearing BALB/C mice

肿瘤免疫学

肿瘤浸润淋巴细胞

CT26 tumors were implanted subcutaneously into syngeneic BALB/C mice and allowed to grow for 15-25 days. Tumors were collected, mechanically dissociated, and immune cells enriched using Percoll gradie

NIAID Data Ecosystem60

Expression data from bone marrow derived- and tumor induced- CD11b+ MDSC

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