Additional file 19 of The genome and transcriptome of the snail Biomphalaria sudanica s.l.: immune gene diversification and highly polymorphic genomic regions in an important African vector of Schistosoma mansoni

Additional file 19: Supplementary Table 18. Results of Biomphalaria sudanica gene family expansion and contraction analysis performed using topGO v2.48.0 [73] in R v4.3.1 [139] with the Weight01 algorithm, node size=10 and statistical test of Fisher (significant p-value ≤ 0.05). The test was performed by comparing the B. sudanica whole genome gene family composition to three separate lists (column=List) of the highly diverse genes identified; 1) ‘All’ 1047 highly diverse genes identified in the B. sudanica genome (as listed Supplementary Table 17), 2) ‘Group-2’ 245 genes classified as immune suspected genes from the highly diverse genes (group 2, Supplementary Table 17), and 3) ‘Group-2-3-4’ 247 genes shortlisted as the protein containing a transmembrane domain (TMD) and categorized in Immune Group 2, 3 (potential role in innate immunity) or 4 (an unknown function but contained TMD(s)) (Supplementary Table 17). Each group contains three tabs, showing gene family expansions and contractions in each set of genes in respects to their Molecular Function (MF), Cellular Component (CC) and Biological Process (BP).