Crystal structure of T. brucei PDE-B1 catalytic domain with inhibitor NPD-937
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Crystal structure of T. brucei PDE-B1 catalytic domain with inhibitor NPD-937 Descriptor: 2-[(4-{5-[(4aR,8aS)-3-cycloheptyl-4-oxo-3,4,4a,5,8,8a-hexahydrophthalazin-1-yl]-2-methoxyphenyl}phenyl)formamido]-N-(2-hydroxyethyl)acetamide, FORMIC ACID, GLYCEROL, ... Authors: Singh, A.K, Anthonyrajah, E.S, Brown, D.G. Deposit date: 2016-06-08 Release date: 2018-03-14 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.14 Å) Cite: Targeting a Subpocket in Trypanosoma brucei Phosphodiesterase B1 (TbrPDEB1) Enables the Structure-Based Discovery of Selective Inhibitors with Trypanocidal Activity. J. Med. Chem., 61, 2018
创建时间：
2016-06-08
