To identify effector genes of pancreatic beta cell failure, we integrated analyses of FoxO1 regulated genes with ChIPseq and RNAseq, super-enhancers, and human type 2 diabetes GWAS loci. Overall desig
NK cells could participate in the pathogenesis process of virus infectious diseases through the inhibitory receptor CD94/NKG2A interacting with HLA-E/virus-derived peptide complex. However, the effect
We studied the effects of polyamine pathway inhibitors on differentiation of nonpathogenic Th17 cellsin vitro. Here, we used difluoromethylornithine (DFMO), an irreversible inhibitor of ODC1, the enzy
Percentages of IFN-γ producing CD56+/CD3− NK cells and CD56+/CD3+ NK-like T cells for each of eight donors after stimulation of CD56+ cells with the indicated cytokines for 48 h.
