Poly (ADP-ribose) polymerase 1 (PARP-1) is a critical enzyme involved in DNA damage repair and recombination, and shows great potential for drug development in the treatment of cancers with defective
This dataset contains RNA sequencing data of cancerous HCT-116 and non-cancerous intestinal IPEC-J2 cells treated with curcumin, three curcumin-based benzothiazepane analogues, and untreated controls.
Aim: Novel thiazole hybrids were synthesized via thiazolation of 4-phenylthiosemicarbazone (4). Materials & methods: The anticancer activity against the NCI 60 cancer cell line panel. Results: Methyl
