five

SLP76 interactome in resting and activated primary mast cells

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NIAID Data Ecosystem2026-03-07 收录
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https://www.omicsdi.org/dataset/pride/PXD000052
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We used a knock-in (KI) mouse expressing SLP-76 with a C-terminal One-Strep-Tag (OST). Such a system allowed the replacement in the genome of SLP-76 by its tagged version and its expression in physiological amounts. Then, by combining high affinity purification and label-free quantitative proteomics, we report here the first description of the SLP76 interactome in resting and activated primary cultured mast cells derived from mice expressing an OST at the C-terminus of SLP-76 (Slp76OST/OST mice).
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2013-08-28
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