Gjc2

ENCODES a protein that exhibits gap junction channel activity (ortholog); gap junction channel activity involved in cell communication by electrical coupling (ortholog); INVOLVED IN negative regulation of G1/S transition of mitotic cell cycle; positive regulation of calcium ion transmembrane transport; positive regulation of gene expression; ASSOCIATED WITH Parkinson's disease; Spinal Cord Injuries; amyotrophic lateral sclerosis (ortholog); FOUND IN gap junction; neuronal cell body; paranode region of axon; INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; 6-propyl-2-thiouracil; amitrole

编码一种展现缝隙连接通道活性（同源）的蛋白质；参与细胞通过电偶联进行通信的缝隙连接通道活性（同源）；在减数分裂细胞周期的G1/S转换负调控中发挥作用；正调控钙离子跨膜转运；正调控基因表达；与帕金森病、脊髓损伤、肌萎缩侧索硬化症（同源）相关；存在于缝隙连接、神经元细胞体、轴突的旁结节区域；与2,2',5,5'-四氯联苯、6-丙基-2-硫尿嘧啶、阿米特罗相互作用。