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In vivo mapping of nucleosomes using psoralen-DNA crosslinking and primer extension.

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PubMed Central1998-03-15 更新2026-05-25 收录
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By the use of psoralen crosslinking and primer extension, a method was developed which allows the analysis of chromatin structure in vivo. Using a yeast minichromosome, >9 nucleosomes were mapped with a resolution of at least +/-30 bp.

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1998-03-15
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