Epigenome analysis of Control and PLX4032 Resistant Clones with EPIC array.. Epigenome analysis of Control and PLX4032 Resistant Clones with EPIC array.
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Genome wide DNA methylation profiling of control and PLX4032 resistant clones to identify resistance-associated methylome alternations, and to integrate with transcriptome analysis. Results provide insight into clonal epigentic adaption of PLX4032 resistance in BRAF V600E melanoma. Overall design: Bisulphite converted DNA from 2 controls (parental and parallel) and 15 PLX4032 resistant clones were hybridised to the Illumina Infinium MethylationEPIC BeadChip.
创建时间：
2019-09-15
